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In a double-blind, placebo-controlled, three-arm study, CS (800 mg/day) reduces pain and improves Lequesne index to the same extend as Celecoxib, a reference NSAIDs currently licenced and marketed for the treatment of knee OA

In addition, the fact that CMS analyzes the data from a regional and even national level, unlike the review performed by the MACs that review a limited subset of hospitals, can facilitate additional editing of the data that may not be readily apparent to the MACs

Pharmaceutics 13 (7), 973 (2021)

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These effects result in edema, demyelination, and peripheral nerve necrosis, impairing nerve conduction

Based on all of the information above, you can see that while its helpful to be aware of individual antioxidants and their benefits, the bigger goal regarding prevention of free radical damage is to focus on consuming a wide variety of nutrient-dense, whole foods