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However, if metformin is still not tolerated, the presence (or absence) of comorbidities helps inform the choice of alternative medications

There are strong familial links, with most patients having first-degree relatives with the disease, and recent genome-wide association studies have identified risk loci[6]

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Raffaele Addeo, Aslnapoli2nord Oncologia, Italy Updates Copyright 2021 Montanino, Manzo, Carillio, Palumbo, Esposito, Sforza, Costanzo, Sandomenico, Botti, Piccirillo, Cascetta, Pascarella, La Manna, Normanno and Morabito
[DOI] [PMC free article] [PubMed] [Google Scholar] 56.Ocansey DKW, Zhang L, Wang Y, Yan Y, Qian H, Zhang X, et al
