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These combination products are designed for daily use on intact skin

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Hammes, W., Schleifer, K
B., and Tan M., Targeting Cellular Metabolism to Improve Cancer Therapeutics, Cell Death & Disease 4, no

Structural analysis of the wild-type HsaGST A2-2 and HsaGST A3-3 shows that the steroid substrate is not binding to HsaGST A2-2 in an orientation compatible with ketosteroid isomerase activity, apparently explaining the different activities of the two enzymes (Tars et al., 2010)

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