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Moreover, OLT1177 preserved the morphological transformation of microglia and significantly inhibited the activation of caspase-1 and the release of IL-1 by inhibiting NLRP3
Gene regulation by transcription factors and microRNAs

Specifically, it restored the increased levels of inflammatory markers and reduced the expression of p-NF-B and phospho-p38 in the brain of AD mice

L., Seifert, S

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