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Tirzepatide is a dual GLP-1 and GIP receptor agonist that can support weight loss, but people with hypothyroidism need specific information about interactions, thyroid function monitoring, and personalized dosing strategies

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As GLP-1 receptor agonists, these peptide drugs mimic the incretin hormone GLP-1, enhancing glucose-dependent insulin secretion, suppressing glucagon release, delaying gastric emptying, and reducing appetite [9]

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Semaglutide can slow stomach emptying and cause constipation, but combining it with laxatives requires careful timing and medical guidance to avoid complications