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It is a member of the TGF- superfamily and is highly expressed across various cancer types (296, 297)

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Mechanistic investigations into vitamin Ds role in mucosal repair via VDR signaling may offer novel therapeutic avenues

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Furthermore, studies have demonstrated that GPR68 deficiency enhances radiotherapy sensitivity and promotes ferroptosis across multiple tumor types [16]

J Biol Chem 1929;82:345-367