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Neff et al., 2021, Wan et al., 2020)

Where Does GLP-1 Fit In

All evaluated GLP-1 RAs led to a significant increase in nausea risk, with orforglipron showing the highest risk, followed by exenatide, tirzepatide, semaglutide, and liraglutide

It will remain available as an inexpensive, short-term option, but it will not improve

A weak association exists between upper gastrointestinal symptoms and the rate of gastric emptying
