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Similarly, TF protected differentiated ARPE-19 from 4HNE toxicity (Supplementary Fig
PA then diffuses back into the bacilli, where it accumulates and exerts multiple effects against Mtb, including inhibition of fatty acid synthase, disruption of membrane potential, and interference with energy production by interacting with ribosomal protein S1 to inhibit trans-translation (Zimhony et al., 2007
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Unprocessed western blots/gels

Small, membrane-permeable, textbook orally-absorbable small molecule

Glutathione agarose beads bind GST-fusion proteins (left), and Protein A, G, and L beads bind to antibodies
