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In both diabetic and non-diabetic patients presenting class II/IV heart failure, GLP-1 infusion led to an improvement of left ventricular (LV) ejection fraction, myocardial ventilation oxygen consumption, 6-min walk distance, and quality of life [50]

Rather, it reflects normal physiological adaptations and the body's attempt to maintain energy homeostasis

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After starting, dose is adjusted every four weeks, blood sugar is monitored, and any emerging weight loss injection side effects are managed proactively