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A stratified next-generation trial could test whether semaglutide works in the right patients even at the same 14 mg dose that failed in an unselected population

In his book, Metabolical, renowned paediatric endocrinologist Dr

How much strength training and walking it takes to protect muscle, starting at 6,000 steps and a 10 to 15 minute post-meal walk

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A new study found that adults with obesity significantly reduced their physical activity while taking GLP-1 medications for weight loss.

In conclusion, the paper provides evidence that the reduction of GLP-1+ cells is a general feature of ileal and colonic inflammation in mice and humans and is likely due to altered epithelial differentiation driven by changes in cellular metabolism, particularly mitochondrial dysfunction.
