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Lower calorie intake can mean fewer vitamins and minerals from food
Glucagon-like Peptide-1 receptor agonists (GLP-1 RA) and metabolic and bariatric surgery (MBS) both improve cardiovascular outcomes in patients with severe obesity and type-2 diabetes (T2D)

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The results suggest long-term success may require more than medication alone.

GLP-1 agonists and dual agonists can cause hypoglycemia, nausea, and more
