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Patients were classified into drug treatment groupssemaglutide versus other antidiabetic medications (insulin, metformin, DPP-4i, SGLT2i, SU, TZD, and other GLP-1RAs)based on the first prescription in the study period (December 2017 to December 2021), which was the baseline or index event

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Incretin based therapies such as GLP-1 receptor agonists have revolutionised management of type 2 diabetes by enhancing insulin secretion, slowing gastric emptying and reducing appetite (Dungan & DeSantis, 2025)

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