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The phentermine versus semaglutide comparison shows that while phentermine-based medications produce less weight loss than GLP-1 agonists, they work through completely different pathways

Accessed February 5, 2025

Gradual titration is standard practice

Medicare and Medicaid Restrictions Federal law prohibits Medicare from covering medications prescribed solely for weight loss

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Studies also show that tirzepatide can potentially decrease liver fat content due to its weight loss effects, possibly improving conditions like fatty liver disease