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In this context, GLP-1 receptor agonists are being hailed as "miracle drugs" with demand far exceeding supply in many markets
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It is a temporal pattern that supports a direct neurological effect rather than an indirect one mediated through body weight changes
It also avoids GIP receptor agonism, whose metabolic consequences remain somewhat controversial (GIP has been characterized as both insulinotropic and adipogenic depending on context)
Many first-time users describe a burst of energy and focus in the first week that they mistake for the appetite suppression itself
