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It may play a positive role in the improvement of various disorders caused by SUD, especially the reduction of sugar intake, alteration of metabolic processes, improvement of neural circuits associated with substance addiction, neuroprotective effects, improvement of glial cell activation, and modulation of gut microbiota (Table 2)

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(1989) UVB irradiation induces melanocyte increase in both exposed and shielded human skin

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It shares the first part of the required biosynthetic enzymes with other flavonoids, such as flavonols and flavanones, and represents a branch of the general phenylpropanoid pathway, whose main precursor is Phe, which itself comes from the shikimic acid pathway (Rasmussen and Dixon, 1999)