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Cancer cells with high glycolytic activity (e.g., tumors with pronounced Warburg effect) have elevated NADH levels, providing sufficient electron donors for FSP1 and enhancing its anti-ferroptotic capacity

Iron homeostasis is further modulated by the IRP-IRE signaling pathway, where iron regulatory proteins (IRP1/2) bind to iron-responsive elements (IREs) in the untranslated regions of ferritin and ferroportin (FPN) mRNAs

Furthermore, the established system for biopsy in BE, requires 4-quadrant biopsies to be taken at every 12 cm length

Shuster LT, Gostout BS, Grossardt BR, Rocca WA

doi: 10.1161/01.RES.66.6.1755 [DOI] [PubMed] [Google Scholar] 142

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