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For example, in a mid-stage human study, people taking higher doses (up to 12mg) lost an average of 24% of their body weight over 48 weeks, which is about 58 pounds for some

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The potent GLP-1 receptor antagonist, exendin-[939] (Ex9), blunted improvements in glucose tolerance in linagliptin-treated control mice and in GcgRAPDX1Cre mice

Methods This retrospective cohort study utilized the TriNetX electronic health record database, a multinational and multi-institutional database