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Some endogenous substrates for CYP2E1 include acetone and fatty acids (which are abundant in the brain) (Lieber 1999)

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PMID: 29358856

PLoS ONE 15 (9), e0238772 (2020)

It has potential benefits in regulating blood sugar levels, making it pertinent to obese people who also have type 2 diabetes or insulin resistance
