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Comprehensive toxicology evaluations reveal that the compound does not affect food intake, body temperature regulation, or basic physiological parameters at effective doses in animal models, indicating that its metabolic effects occur through specific pathway modulation rather than general physiological disruption

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doi: 10.1016/j.actbio.2020.12.046 Summary Keywords Nrf2, periodontal disease, lipid peroxidation, apoptosis, bone homeostasis Citation Ma F, Luo S, Lu C, Jiang X, Chen K, Deng J, Ma S and Li Z (2022) The role of Nrf2 in periodontal disease by regulating lipid peroxidation, inflammation and apoptosis

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