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The 4mg tier is also the lowest maintenance dose being tested in the Phase 3 TRIUMPH program, which signals that the sponsor considers it the minimum effective dose for a regulatory filing

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Data show that there were 1,176 cases of acute and chronic pancreatitis following tirzepatide use reported between January 2023 and June 2026, 18 of which had a fatal outcome

focus on monthly trends rather than day-to-day changes