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Additionally, within the central nervous system (CNS), GLP-1 administration has been associated with an anorectic response, although the precise mechanisms remain to be fully elucidated

It will be difficult to engineer balanced agonism into a single small-molecule because the sequence hybridisation of the dual and triple peptide agonists has no obvious chemical analogue

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November 26, 2020

Insulin Sensitivity Evidence A systematic review and meta-analysis of randomized controlled trials published in Pharmacological Research found that oral magnesium supplementation improved insulin sensitivity and glucose control markers (PMID: 27329332)

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