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It also modulates the activity of metalloproteinases (enzymes that break down extracellular matrix proteins) and their inhibitors, creating a balanced environment where damaged tissue is cleared while new tissue is being built

doi: 10.2174/09298673113209990226 242 RichmondAYingjunS

Signals from the SCN are converted into circadian oscillations through the output pathway

doi: 10.1016/j.jaut.2019.06.010 16

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These advances could mark the beginning of a new era in the early detection and monitoring of MASLD progression [129]