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Moreover, there were significant differences in body weight between the NC group and the GLP-1RAs@NPs group

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Recent phase 2 studies of CagriSema, a once-weekly combination of cagrilintide (an amylin analogue) and semaglutide, and triple-hormone (GLP1, GIP, glucagon) receptor agonist, retatrutide, demonstrated an average 2%-2.2% reduction in HbA 1c at 24 weeks and a mean 16%-17% reduction in body weight (with the highest doses) at 32-36 weeks in those with obesity and T2D [70,71]
