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A small human proof-of-concept trial reported that semaglutide reduced vastus lateralis cross-sectional area but did not reduce knee-extension strength or grip strength over 12 weeks

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Recent Findings Since semaglutide may cause delayed gastric emptying and residual gastric contents, controversies arise on preoperative medication management, adequate preoperative fasting periods, utilization of gastric ultrasound, and rapid sequence induction and intubation to mitigate the risks of regurgitation and pulmonary aspiration of gastric contents during anesthesia care

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