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Elevated TMAO levels were connected to severe illness states and a poor prognosis, with higher levels indicating worse outcomes even when controlling for confounders

In the method of the present invention, a composition as described hereinabove may be ingested as a food supplement, dietary supplement, nutritive supplement, or medical food

9) However, a recent study examined the prevalence of heterozygotes for SLC22A5 mutations in 324 patients with cardiomyopathy and demonstrated that heterozygosity for PCD is not more frequent in patients with unselected types of cardiomyopathy and is unlikely to be an important cause of cardiomyopathy

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It is widely known that mitochondrial dysfunction (high ROS production, apoptotic cells, decreased m, and low cellular ATP levels) boosts the pathogenesis of KOA because it involves lipid homeostasis and cytokine release and promotes cell apoptosis [14, 15]