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The physiological effects of PYY are mediated through a family of NPY receptors (termed Y1, Y2, Y3, Y4, and Y5), which are differentially expressed in a wide range of tissue including enterocytes, myenteric and submucosal neurons and extrinsic primary afferent nerve fibers (123)

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However, the oral formulation still offers significant benefits, making it a viable option for those who prefer not to inject

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