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IV hangover therapy works by delivering a carefully balanced combination of fluids, electrolytes, vitamins, and medications directly into your bloodstream

If you have a history of B12 deficiency, malabsorption issues, or are vegetarian/vegan with marginal B12 status, the weekly B12 injection provides protection during the high-risk period of rapid weight loss

Active B12: Each capsule provides 1 mg vitamin B12 as methylcobalamin, which is more efficiently used by the body compared to other forms of vitamin B12, like cyanocobalamin Heart & Brain Health: Supports a normal level of homocysteine in the body to benefit healthy cardiac function, blood cell formation, and optimal nerve function* Sleep Support: Helps maintain normal circadian rhythms to support restful sleep and supports healthy methylation processes in the body* Third-Party Certified: This product has been third-party tested and certified to verify what's in the package matches what's on the label and to confirm it contains no unsafe levels of contaminants Trusted: Thorne is trusted by 100+ professional sports teams and the #1 most recommended clinical brand by consumers and health-care practitioners (Based on a 2026 independent survey of US supplement consumers and health-care practitioners)

In the weight loss context specifically, B12 injections are a standard component of metabolic support programs included in the Phentermine program package and used alongside lipotropic injections and GLP-1 medications

Burton, B

There is evidence that the peptide restricts NNMT function, improving fat-burning