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Patients usually interpret some symptoms as adverse events due to treatment, instead of symptoms related to smoking cessation

Escalating safety concerns are not changing adolescent e-cigarette use patterns: The possible role of adolescent mental health

Indeed, when nicotine is administered concurrently with a CYP2A6 inhibitor of unknown strength, the substrate metabolism will be reduced, resulting in increasing serum concentrations and heightened risk, incidence, and/or severity of ADRs

2b, Supplementary Table 2)

We strongly recommend against several interventions where data on effectiveness for smoking cessation were lacking

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