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55 This finding may be explained at least in part by reduced expression of the soluble guanylyl cyclase (sGC), as in different hypertensive animal models, the expression of one or both sGC subunits ( 1 and 1 ), as well as NO-dependent sGC activity were significantly decreased

Elevated lactate levels promote Treg cell proliferation and enhance OXPHOS functions [112]

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doi: 10.1001/jama.257.17.2303 [DOI] [PubMed] [Google Scholar] 140

Standardized outcome measurement facilitates assessment of individual patient response and contributes to broader understanding of clinical efficacy