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doi: 10.1371/journal.pgen.1010436

Overall, the therapeutic potential of L-carnitinebased combination strategies is most likely to be maximized when they are tailored to specific pathological contexts and concurrently target key processes such as fatty acid oxidation, insulin signaling, oxidative stress, and gut barrier integrity (92)

Phenols with a nonpolar side chain in the para (or 4-) position, and in particular an ether group at that position, appear to be the most potent depigmenting chemicals 66