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While there is no clear evidence that semaglutide directly harms the eyes, there are some potential concerns about how the drug might affect eye health, particularly in people with conditions like glaucoma

Trulicity Other medication options If youre thinking about stepping off GLP-1s entirely, there are several nonGLP-1 medications that may still offer help with appetite and metabolism

The Precision Peptide Genetic Test analyzes 14 pathways and 150+ genetic insights related to digestive function and inflammatory response, including variants that affect acid sensitivity and GI motility

Future GLP-2 trials in IBD should stratify patients by disease phenotype (mucosal UC, inflammatory CD, stricturing CD) and incorporate serial cross-sectional imaging to monitor for stricture progression, given the mechanistic link between GLP-2R signaling through subepithelial myofibroblasts and intestinal fibrogenesis

This combination can cause internal bleeding that may be difficult to stop

doi: 10.1016/S0065-2776(08)60404-6 50 ConstantinescuCSFarooqiNOBrienKGranB