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Dry and pruritic skin is a common clinical manifestation of SS, with vasculitis being the second most common cutaneous manifestation, and histological examination usually confirms the diagnosis of leukocytoclastic vasculitis (LCV) [284]

Last years award for paleogenomics falls more toward the former, suggesting an advance with a more clinical focus could well be in the Nobel Assemblys sights this year

Chronic low-grade inflammation, characterized by elevated levels of cytokines such as TNF- and IL-6, is frequently observed in patients with mood disorders and metabolic dysregulation [26,82,83]

In another study conducted in 2022, nearly half (48.6%) of Americans taking semaglutide (such as Ozempic and Wegovy) reported experiencing adverse effects

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