glp 1 agonist fda approval In a major milestone for obesity care, the has approved Wegovy® as the first oral GLP-1 receptor for chronic weight management in adults with obesity or overweight and related conditions Patient education tips for GLP-1,

showed that liraglutide improves the renal endothelial dysfunction in obese Zucker rats on a high-salt diet by increasing the renal eNOS expression (Sukumaran et al., 2019)

Author contributions In the experiment, WW completed the main operation of the experiment, QX, YG, and HW participated in the experiment and provided technical guidance for the experiment, HD and FL provided guidance for the experimental scheme, and FY provided financial support and detailed arrangement for the experimental plan

Pharmacol Ther 113:546593 Moffett RC, Patterson S, Irwin N, Flatt PR (2015) Positive effects of GLP-1 receptor activation with liraglutide on pancreatic islet morphology and metabolic control in C57BL/KsJ db/db mice with degenerative diabetes

doi: 10.1111/j.1463-1326.2011.01364.x 109 DunganKMPovedanoSTForstTGonzlezJGGAtissoCSeallsWet al

(2023) Sodium-glucose transport protein 2 (SGLT2) inhibitors

19 The Effect of GLP-1RAs on Blood Pressure A meta-analysis of 16 RCTs showed that use of GLP-1RAs leads to a moderate BP reduction in patients with hypertension