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The -GCS-catalysed formation of -glutamylcysteine is the first and rate-limiting step in de novo GSH synthesis and is feedback-inhibited by GSH, a mechanism that is central to the regulation of cellular GSH concentrations (7)

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Wu, Z., Zhao, L., Chen, X., Cheng, X

Whether you're seeking general antioxidant support or addressing specific health goals, the scientific foundation supporting L-Glutathione continues to strengthen with each passing year

Glutathione synthesis is regulated mainly by the availability of precursor cysteine and the concentration of glutathione itself which feeds back to regulate its own synthesis

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