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Can Microdosing GLP-1s Promote Health And Weight Loss

[DOI] [PubMed] [Google Scholar] 30.Deacon C.F

Indeed, a combination of peptide mutagenesis to eliminate the glucagon activity from oxyntomodulin, combined with studies in Glp1r / mice or WT mice using a GCGR antagonist, have highlighted the importance of both the GCGR and GLP-1R for the maximal weight loss effect ensuing from oxyntomodulin administration [43]

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Of the study cohort, 92% had type 2 diabetes and 86% had obesity