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Description
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In the human trial, the design was simpler still: 55 participants with obesity were randomized to receive either Tirzepatide or a placebo for 18 weeks

2023 doi: 10.1016/j.cjca.2025.03.011

[DOI] [PMC free article] [PubMed] [Google Scholar] 61.Turton MD, OShea D, Gunn I, Beak SA, Edwards CM, Meeran K, Choi SJ, Taylor GM, Heath MM, Lambert PD, et al

In the phase 3 OASIS 4 trial, adults taking a 25 mg daily dose of oral semaglutide lost an average of 13.6% of their body weight, compared with a placebo
