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Pharmacokinetic comparisons indicate that intranasal delivery of exenatide or dulaglutide leads to preferential accumulation in the hippocampus and neocortex within 30 min, with higher regional exposure than intravenous administration, even in amyloid precursor protein/presenilin 1 mice ( APP /PS1) transgenic mice [278]

0.56 (95% CI, 0.55-0.56) for semaglutide

It is essential to view these dietary and lifestyle changes not as a temporary "diet" undertaken solely while on medication, but as the foundation for long-term health and well-being

doi: 10.1038/s41422-020-0291-z 95 PedersenH

95% CI 0.79 1.16

This is not a one-size-fits-all therapy