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52 While the direct response of L-cells to secrete GLP-1 in reaction to luminal nutrients is acknowledged, it could be recognized as the principal process behind GLP-1 secretion

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Discontinuation rates due to adverse events remain comparable, but strict adherence to a slow, methodical titration schedule is vital for both compounds

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A series of 3-5 treatments at 1-4 weeks apart may be required to achieve the desired results

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Oral semaglutide tablets are FDA-approved for type 2 diabetes (Rybelsus)

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