dpp-4 inhibitor and glp-1 receptor agonist combination GLP-1-RA inhibitors in the management of type 2 diabetes DPP4 Inhibitors vs GLP-1 Agonists

The investigators are assessing a three-point major adverse cardiovascular event endpoint (myocardial infarction, stroke, and cardiovascular death), over an estimated maximum of 54months (NCT04255433, estimated study completion in October 2024)

On the other hand, Wegovy and Ozempic, which contain Semaglutide GLP-1 , primarily focus on mimicking the GLP-1 hormone to induce satiety and reduce food intake

14-17 GLP-1RAs decrease RGC damage by preventing mitophagy in diabetic rat models and, in vitro, demonstrating the neuroprotective effects of these medications on the retina

Nonetheless, residual effects on gastric emptying could still produce significant gastrointestinal adverse effects in patients treated with long-acting GLP-RAs (167)

My husband says, Oh wow, you look like what you looked like when I met you.' Tori Spelling, 53 Tori Spelling revealed that she had turned to GLP-1 medications, Ozempic and Mounjaro to help her lose the baby weight after the birth of her fifth child, Beau, in 2017

doi: 10.1016/j.jdiacomp.2014.01.012 73 BolliGBMunteanuMDotsenkoSNiemoellerEBokaGWuYet al