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2016;9(1):64] Wadden TA, Hollander P, Klein S, et al

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Most trials are randomized and blinded, meaning some participants receive retatrutide, while others get a placebo that doesnt include the active ingredients

De Araujo is finding that adverse reactions might be caused by how the drug differs from the naturally occurring peptide hormone: The hormone acts mostly locally and degrades quickly, while the medicine works mainly on the brain and is designed to stick around in the body

But the benefits may not last after people stop taking the drugs, according to Dr

Further in vitro studies in IEC-6 cells revealed that exendin-4 enhanced SERT expression and increased 5-HT reuptake [58] (Fig