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In this manner, GLP-1R agonist therapies provide glucose lowering effects with the additional benefit of a lower limit for glucose concentrations, consistent with glycaemic safety

When clinically appropriate, our Fishers providers may prescribe GLP-1 medications including semaglutide and tirzepatide as part of a physician-supervised weight loss program

When expanding trial eligibility criteria to reflect broader patient populations typically encountered in clinical practice, we identified 453,201 individuals initiating semaglutide or sitagliptin (expanding SUSTAIN-6 eligibility) and 136,089 initiating tirzepatide or dulaglutide (expanding SURPASS-CVOT eligibility)

Role of Tirzepatide in T2DM and Obesity Management 2.1

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