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doi: 10.1172/JCI25083 14 CastagnaMGDenticeMCantaraSAmbrosioRMainoFPorcelliTet al

Lastly, a new diagnostic algorithm [H 2 FPEF score(Reddy et al., 2018)] that defines the most relevant clinical features (obesity, hypertension, atrial fibrillation, pulmonary hypertension, aging and diastolic dysfunction) of HFpEF has been recently developed (Figure 1)

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They were then stored at different temperatures (7C, 10C, and 15C) for 15 days

These are local anesthetics that will numb the area immediately to reduce needle pain, and then relax the tight muscles of the nodule