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Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in crohn disease and experimental colitis in vivo

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This activation triggers pathways such as PI3K/Akt, TGF-1/p38-MAPK, and NF-B, resulting in endothelial cell apoptosis, inflammation, autophagy, and fibrosis

Tumor cells suppress radiation-induced immunity by hijacking caspase 9 signaling
