how to fuel workouts on glp-1 GLP-1s and Strength Training: Preserve Muscle in Bellevue & Redmond — bStrong Personal Training The Disconnect Between GLP-1 Drugs

This makes them ideal locations for a shot that needs to be injected just under the skin, as opposed to an intramuscular injection that needs to go past layers of skin and fat to get deep into a muscle

They bind to the same receptors but resist the enzymatic breakdown (by DPP-4) that rapidly degrades natural GLP-1

Rosenstock J., Reusch, J., Bush, M., Yang, F

These receptors become stimulated from many substances, including heroin, prescription pills and other opioids

Your skin acts as a protective barrier, and even if small amounts of these compounds did get absorbed, research doesnt support that they would have any appetite-suppressing effects

The Case for Patchie Patchie offers a convenient, low-commitment entry point for people interested in botanical appetite support as part of their 2026 wellness goals