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This adds another layer of complexity to dosage calculations, because timing, potential interactions, and total injection volume all need consideration

doi:10.1155/2017/1297658 Nordio M, Pajalich R

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Lactate increases in the joint of animals with aseptic polysinovisits, inducing a metabolic reprogramming of FLS and increasing the expression of glycolytic enzymes and pro-inflammatory molecules like TNF- 24

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