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Utilizing Technology to Enhance Patient Safety Measures Technology plays a transformative role in enhancing patient safety in clinical trials

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Clinical validation: high IGF-axis activity correlates with PD-L1 expression and poor immune infiltration Analysis of TCGA prostate adenocarcinoma data (n = 498) showed that tumors in the highest quartiles of IGF1 or IGFBP5 expression had significantly higher CD274 (PD-L1) levels

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In vivo , DHLA has been shown to stimulate the Ca 2+ -induced mitochondrial permeability transition (MPT) in rat liver mitochondria, which was inhibited by the radical scavenger butylhydroxytoluene, suggesting that DHLA-induced MPT may be due to ROS production [44]

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