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Administration: Do not aspirate for subcutaneous injections [11]

Cardiovascular benefits: Demonstrated in outcome trials, including reduced risk of major adverse cardiovascular events [6]

For example, PMPRB will consider the highest price in the reference basket rather than the median, and due to court rulings, it cannot factor pharmacoeconomic value or market size into its price reviews

Supplementary information The online version contains supplementary material available at 10.1038/s41421-024-00700-0

Autophagosome/lysosome analysis myt-1(pan8) I animals were crossed with DA2123 ( adIs2122 [lgg-1p:GFP:lgg-1 + rol-6(su1006) ]) (52) or MAH215 ( sqIs11 [ lgg-1p:mCherry:GFP:lgg-1 + rol-6(su1006) ]) worm strains and autophagosomal pool size was evaluated in adult worms compared to control animals of the same age (3-day-old worms or L4/young adult stage, respectively), in basal fed conditions or after 24-hour starvation with agitation at room temperature in M9 buffer

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