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demonstrated that in neuronal cells that tirzepatide activates Akt/CREB/BDNF pathway and the downstream signaling cascade counteracting hyperglycemia and insulin resistance-related damage at the neuronal level (51)

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[DOI] [PubMed] [Google Scholar] 104.VI N.B., Tressler E.H., Vendruscolo L.F., Leggio L., Farokhnia M

additionally, the concept of insulin neuritis is rather similar, linked to a rapid decline in hyperglycemia [43]
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