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It can be argued that PPAR modulation is an essential mediator of these present findings and PPAR-beta activation seems to be decisive to restore liver homeostasis, with structural liver cell enhancement

Transcripts inversely regulated on AR-v19 depletion and overexpression are associated RNA processing and metabolism Comparison of AR-v19 k/d and AR-v19 overexpression transcriptomes identified transcripts that were exclusively altered in each data set (AR-v19 depletion-green, AR-v19 overexpression purple), transcripts inversely regulated, upregulated following AR-v19 depletion, downregulated on AR-v19 overexpression (303, light purple) or downregulated on AR-v19 depletion and upregulated on AR-v19 overexpression (370, light green) and transcripts commonly altered in both datasets (grey) (Fig