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High-fat hypercaloric diet induces obesity, glucose intolerance and hyperlipidemia in normal adult male Wistar rat

Furthermore, mitochondrial impairment can, in turn, disrupt endolysosomal processes, as endolysosomal biogenesis may be modulated in response to mitochondrial damage (Fernandez-Mosquera et al., 2017)

[DOI] [PubMed] [Google Scholar] 203.Yalamandala BN, et al

Oral semaglutide may cause slightly more GI effects due to stomach exposure, while injections bypass the GI tract initially

Behavioral strategies proven effective for weight maintenance include consistent self-monitoring of weight (at least weekly), food logging, regular meal patterns, and cognitive behavioral techniques to address emotional eating and environmental triggers